Osmosis Jones

Osmosis Jones is a 2001 American liveactionanimated buddy cop comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the liveaction ones. Unusual in this genre, the animated characters are inside the liveaction ones the film is set in a fictionalized version of the human body which resembles a large city, where microorganisms or any being based in organisms are anthropomorphic and centers on Frank Detorre, a slovenly zookeeper. Osmosis Jones, a white blood cell, teams up with Drix, a cold pill, against Thrax, a deadly virus who plans to kill Frank in fortyeight hours and other characters living within him.

Frank Detorre Bill Murray is a widowed unkempt zookeeper at the Sucat Memorial Zoo in Rhode Island. Much to the frustration of his young daughter, Shane Elena Franklin, he eats compulsively unhealthy and has minimal concern for germs or disease. While trying to eat a hardboiled egg with mayonnaise and salt, it is stolen from him by a chimpanzee. He gets it back, but not before it falls into the filth of the chimps habitat. When Shane is disgusted by him about to eat it he uses the ten second rule as a justification for the unsanitary act.Inside Franks body, Osmosis Ozzy Jones Chris Rock, an agent of the Frank PD, is an adventureseeking white blood cell with a good sense of humor. He is a rebel cop, frequently disobeying authority to do what he thinks is right. He is often mocked by his fellow cops due to his rebellious nature. He has been relocated to the mouth to fight against germs entering the body via ingestion after he induced Frank to vomit all over Shanes science and P. E. teacher, Mrs. Boyd Molly Shannon at the schools science fair. This was considered a false alarm because he had been the only one to suspect an incoming pathological threat from the raw oyster that Frank had eaten from one of the displays. After several newcomer germs, believed to be gingivitis, hijack a squad car in the mouth, Ozzy and another officer in an FPD helicopter are pulled into the lungs by a massive yawn while in pursuit. After the germs evade capture and pass into Immunitys jurisdiction, Ozzy disobeys direct orders as he pursues the germ on foot and accidentally triggers a major cramp in Franks leg. ........

Source: Wikipedia